Streptozocin

Cat. No. 1621

Streptozocin C8H15N3O7 [18883-66-4]

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Alternative Name: Streptozotocin

Chemical Name: 2-Deoxy-2-[[(methylnitrosoamino)carbonyl]amino]-D-glucose

Biological Activity

Antibiotic and antitumor agent. Alkylates DNA and induces diabetes mellitus via reduction of nicotinamide adenine dinucleotide in pancreatic β-cells in vivo.

Technical Data

M.Wt:
265.22
Formula:
C8H15N3O7
Solubility:
Soluble to 100 mM in water and to 100 mM in DMSO
Purity:
>95 %
Storage:
Store at -20°C
CAS No:
18883-66-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Weis (1982) Steptozotocin: A review of its pharmacology, efficacy and toxicity. Cancer Treat. Rep. 66 427. PMID: 6277485.

Bennett and Pegg (1981) Alkylation of DNA in rat tissues following administration of streptozotocin. Cancer Res. 41 2786. PMID: 6454479.

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Keywords: Streptozocin, supplier, DNA, alkylators, antitumor, antitmour, induces, diabetes, Apoptosis, Inducers, antibiotics, chemotherapeutics, Tocris Bioscience, Apoptosis Inducing products

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