Cat. No. 2733
Chemical Name: 11-Chloro-5-(5-cyclopropyl-1,2,4-ox
Biological ActivityGABAA receptor ligand that binds with comparable affinities to three receptor subtypes: α1β2γ2, α3β2γ2 and α6β2γ2 (Ki values are 7.8, 9.5 and 11.0 nM respectively). Potentiates GABA-induced chloride currents in α6β2γ2 receptors. Sedative/hypnotic compound.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Tang et al (1995) U-90042, a sedative/hypnotic compound that interacts differentially with the GABAA receptor subtypes. J.Pharmacol.Exp.Ther. 275 761. PMID: 7473164.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses U 90042 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: U 90042, supplier, GABAA, receptor, ligands, Receptors, U90042, Tocris Bioscience, GABAA Receptor Modulator products
Find multiple products by catalog number
December 13 - 15, 2016