Spinorphin

Cat. No. 2931

Spinorphin Leu-Val-Val-Tyr-Pro-Trp-Thr

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Biological Activity

Endogenous peptide; inhibits enkephalin-degrading enzymes (aminopeptidase, dipeptidyl aminopeptidase III, neprilysin) and angiotensin-converting enzyme. Displays antinociceptive effects in mice.

Technical Data

M.Wt:
877.05
Formula:
C45H64N8O10
Sequence:
LVVYPWT
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
137201-62-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Honda et al (2001) Spinorphin, an endogenous inhibitor of enkephalin-degrading enzymes, potentiates Leu-enkephalin-induced anti-allodynic and antinociceptive effects in mice. Jpn.J.Pharmacol. 87 261. PMID: 11829145.

Liang et al (2001) The endogenous opioid spinorphin blocks fMet-Leu-Phe-induced neutrophil chemotaxis by acting as a specific antagonist at the N-formylpeptide receptor subtype FPR. J.Immunol. 167 6609. PMID: 11714831.

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Keywords: Spinorphin, supplier, Potent, P2X3, antagonists, Enkephalin-degrading, ACE, inhibitors, inhibits, Receptors, Purinergic, purinoceptors, Angiotensin-Converting, Enzyme, Proteinases, Proteases, Tocris Bioscience, Angiotensin-Converting Enzyme Inhibitor products

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