Cat. No. 2947
Chemical Name: 4-(1H-Imidazol-4-ylmethyl)-1-methyl
Biological ActivityExtremely selective histamine H3 receptor agonist (pKi values are 9.0, 5.7, < 5.0 and < 5.0 for hH3, hH4, hH1 and hH2 receptors respectively). Potently inhibits EFS-evoked contractions of guinea pig ileum (pD2 = 8.26).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Kitbunnadaj et al (2005) N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist. J.Med.Chem. 48 2100. PMID: 15771452.
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Keywords: Methimepip dihydrobromide, supplier, selective, H3, agonists, Receptors, Histamine, histaminergic, Tocris Bioscience, Histamine H3 Receptor Agonist products