Cat. No. 2947
Chemical Name: 4-(1H-Imidazol-4-ylmethyl)-1-methyl
Biological ActivityExtremely selective histamine H3 receptor agonist (pKi values are 9.0, 5.7, < 5.0 and < 5.0 for hH3, hH4, hH1 and hH2 receptors respectively). Potently inhibits EFS-evoked contractions of guinea pig ileum (pD2 = 8.26).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Kitbunnadaj et al (2005) N-substituted piperidinyl alkyl imidazoles: discovery of methimepip as a potent and selective histamine H3 receptor agonist. J.Med.Chem. 48 2100. PMID: 15771452.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Methimepip dihydrobromide from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Methimepip dihydrobromide, supplier, selective, H3, agonists, Receptors, Histamine, histaminergic, Tocris Bioscience, Histamine H3 Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
High affinity H1 antagonist; anti-inflammatory.
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.