Apelin-17 (human, bovine)

Cat. No. 3007

Apelin-17 (human, bovine) Lys-Phe-Arg-Arg-Gln-Arg-Pro-Arg-Leu-Ser-His-Lys-Gly-Pro-Met-Pro-Phe

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Alternative Names: K17F, Prepro-61-77-Apelin

Biological Activity

Endogenous apelin receptor agonist. Potently inhibits forskolin-stimulated cAMP accumulation (pIC50 = 9.94).

Technical Data

M.Wt:
2138.56
Formula:
C96H156N34O20S
Sequence:
KFRRQRPRLSHKGPMPF
Solubility:
Soluble to 1.20 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
217082-57-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

De Mota et al (2004) Apelin, a potent diuretic neuropeptide counteracting vasopressin actions through inhibition of vasopressin neuron activity and vasopressin release. Proc.Natl.Acad.Sci. USA 101 10464.

Medhurst et al (2003) Pharmacological and immunohistochemical characterization of the APJ receptor and its endogenous ligand apelin. J.Neurochem. 84 1162. PMID: 12603839.

Tatemoto et al (1998) Isolation and characterization of a novel endogenous peptide ligand for the human APJ receptor. Biochem.Biophys.Res.Comms. 251 471.

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Keywords: Apelin-17 (human, bovine), supplier, Endogenous, APJ, receptor, agonists, Receptors, Apelin, adipokines, Tocris Bioscience

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