Cat. No. 2764
Chemical Name: N-(Piperidin-1-yl)-1-(2,4-dichlorop
Biological ActivityHighly selective CB2 receptor agonist; Ki values are 0.037 and 363 nM for CB2 and CB1 receptors respectively. Increases P-ERK1/2 expression in HL-60 cells in vitro.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Tschop et al (2009) The cannabinoid receptor 2 is critical for the host response to sepsis. J.Immunol. 183 499. PMID: 19525393.
Murineddu et al (2006) Tricyclic pyrazoles. 4. Synthesis and biological evaluation of analogues of the robust and selective CB2 cannabinoid ligand 1-(2',4'-dichlorophenyl)-6-methyl-N-piperidin-1-yl-1,4-dihydroindeno[1,2-c]pyrazole-3-carboxamide. J.Med.Chem. 49 7502. PMID: 17149879.
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Keywords: GP 1a, supplier, selective, CB2, receptor, agonists, cannabinoid, receptors, GP1a, cb2r, Tocris Bioscience, CB2 Receptor Agonist products