RU 26752

Cat. No. 2970

RU 26752 C25H36O3 [76676-33-0]

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Chemical Name: (7α,17α)-17-Hydroxy-3-oxo-7-propylpregn-4-ene-21-carboxylic acid γ-lactone

Biological Activity

Mineralocorticoid receptor antagonist. Prevents aldosterone-induced hypertension in rats.

Technical Data

M.Wt:
384.55
Formula:
C25H36O3
Solubility:
Soluble to 25 mM in DMSO
Purity:
>99 %
Storage:
Store at -20°C
CAS No:
76676-33-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Huyet et al (2007) Structural basis of spirolactone recognition by the mineralocorticoid receptor. Mol.Pharmacol. 72 563. PMID: 17569793.

Kalimi et al (1990) Effects of antimineralocorticoid RU 26752 on steroid-induced hypertension in rats. Am.J.Physiol. 258 E737. PMID: 2333987.

Lazar and Agarwal (1986) Evidence for an antagonist specific receptor that does not bind mineralocorticoid agonists. Biochem.Biophy.Res.Comms. 134 261.

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Citations are publications that use Tocris products.

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Keywords: RU 26752, supplier, Mineralocorticoid, receptors, antagonists, Aldosterone, RU26752, Tocris Bioscience, Mineralocorticoid Receptor Antagonist products

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