Cat. No. 2959
Chemical Name: 1,4-Dihydro-2,6-dimethyl-4-(3-nitro
Biological ActivityL-type Ca2+ channel blocker that displays higher vascular selectivity than felodipine (Cat. No. 2960). Causes peripheral vasodilation with only weak negative inotropic activity. Antihypertensive.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Wirtz and Herzig (2004) Molecular mechanisms of vasoselectivity of the 1,4-dihydropyridine lercanidipine. Br.J.Pharmacol. 142 275. PMID: 15155536.
Bang et al (2003) Lercanidipine. A review of its efficacy in the management of hypertension. Drugs 63 2449. PMID: 14609358.
Sironi et al (1996) Antihypertensive effects of lercanidipine in experimental hypertensive rats and dogs. Arzneim.Forsch. 46 152.
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Keywords: Lercanidipine hydrochloride, supplier, Ca2+, channel, blockers, L-type, Calcium, CaV, Channels, L-Type, voltage-gated, voltage-dependent, Tocris Bioscience, Voltage-gated Calcium Channel (CaV) Blocker products