Cat. No. 2940
Alternative Name: Platelet-activating factor
Chemical Name: (7R)-7-(Acetyloxy)-4-hydroxy-N,N,N-
Biological ActivityEndogenous platelet-activating factor (PAF) and ligand for PAF receptors. Produced by inflammatory cells and a potent chemoattractant for polymorphonuclear neutrophils. Induces increased vascular permeability.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Handa et al (1991) Vasorelaxant effect of C16-PAF and C18-PAF on renal blood flow and systemic blood pressure in the anesthetized rat. Life Sci. 49 747. PMID: 1875784.
Archer et al (1988) Actions of platelet activating factor (PAF) homologues and their combinations on neutrophil chemokinesis and cutaneous inflammatory responses in man. J.Invest.Dermatol. 91 82. PMID: 3385217.
Oda et al (1985) Molecular species of platelet-activating factor generated by human neutrophils challenged with ionophore A23187. J.Immunol. 134 1090. PMID: 3917470.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses PAF (C16) from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: PAF (C16), supplier, Endogenous, platelet-activating, factor, PAF, Receptors, Platelet-activating, Factor, Tocris Bioscience, Platelet-Activating Factor (PAF) Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Selective GPR84 agonistIHR-Cy3
Potent fluorescent Smo antagonistRo 6842262
Potent LPA1 antagonistAMG 853
Potent dual CRTH2 and prostaglandin D2 (PGD2) receptor antagonistAM 4668
Potent FFA1 (GPR40) agonistCATPB
FFA2 antagonist/inverse agonistOleanolic acid
Selective GPBA receptor (TGR5) partial agonistPPTN hydrochloride
High affinity and selective P2Y14 antagonistItraconazole
SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)SAR 216471 hydrochloride
Potent P2Y12 antagonist; orally availableA 971432
Potent and selective S1P5 agonistGLPG 0974
Potent FFA2 antagonist
One Day Symposium
March 1, 2017
Amsterdam, The Netherlands