CRF (6-33)

Cat. No. 1607

CRF (6-33) Ile-Ser-Leu-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Glu-Val-Leu-Glu-Met-Ala-Arg-Ala-Glu-Gln-Leu-Ala-Gln-Gln-Ala-His-Ser

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Alternative Name: Corticotropin-Releasing Factor (6-33)

Biological Activity

Corticotropin-releasing factor binding protein (CRFBP) inhibitor peptide; displaces CRF from CRFBP. Suppresses body weight gain and increases motor activity in obese rats in vivo.

Licensing Information

Sold with the permission of the SALK Institute

Technical Data

M.Wt:
3220.68
Formula:
C141H231N41O43S
Sequence:
ISLDLTFHLLREVLEMARAEQLAQQAHS
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
120066-38-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Jahn et al (2002) The binding protein of corticotropin-releasing factor: ligand-binding site and subunit structure. Proc.Natl.Acad.Sci.U.S.A. 99 12055. PMID: 12215497.

Heinrichs et al (2001) Dissociation of arousal-like from anxiogenic-like actions of brain corticotropin-releasing factor receptor ligands in rats. Behav.Brain Res. 122 43. PMID: 11287075.

Heinrichs et al (2001) Selective stimulatory actions of corticotropin-releasing factor ligands on correlates of energy balance. Physiol.Behav. 74 5. PMID: 11564446.

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Keywords: CRF (6-33), supplier, CRF-binding, protein, inhibitors, inhibits, Corticotropin-Releasing, Factor, Non-Selective, Receptors, Corticotropin, Releasing, (6-33), Tocris Bioscience, Non-selective CRF Receptor products

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