Urocortin (human)

Cat. No. 1604

Urocortin (human) Asp-Asn-Pro-Ser-Leu-Ser-Ile-Asp-Leu-Thr-Phe-His-Leu-Leu-Arg-Thr-Leu-Leu-Glu-Leu-Ala-Arg-Thr-Gln-Ser-Gln-Arg-Glu-Arg-Ala-Glu-Gln-Asn-Arg-Ile-Ile-Phe-Asp-Ser-Val-NH2

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Biological Activity

Endogenous CRF agonist. Ki values are 0.4, 0.3 and 0.5 nM for hCRF1, rCRF2α and mCRF2β respectively.

Licensing Information

Sold with the permission of the SALK Institute

Technical Data

M.Wt:
4696.29
Formula:
C204H337N63O64
Sequence:
DNPSLSIDLTFHLLRTLLELARTQSQRERAEQNRIIFDSV

(Modifications: Val-40 = C-terminal amide)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
176591-49-4

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
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Safety Data Sheet: View Safety Data Sheet

Reul and Holsboer (2002) Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr.Opin.Pharmacol. 2 23. PMID: 11786305.

Skelton et al (2000) The neurobiology of urocortin. Regul.Pept. 93 85. PMID: 11033056.

Perrin and Vale (1999) Corticotropin releasing factor receptors and their ligand family. Ann.N.Y.Acad.Sci. 885 312. PMID: 10816663.

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Keywords: Urocortin (human), supplier, Endogenous, CRF, agonists, Corticotropin-Releasing, Factor, Non-Selective, Receptors, Tocris Bioscience, Non-selective CRF Receptor Agonist products

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