Cat. No. 1604
Biological ActivityEndogenous CRF agonist. Ki values are 0.4, 0.3 and 0.5 nM for hCRF1, rCRF2α and mCRF2β respectively.
Licensing InformationSold with the permission of the SALK Institute
(Modifications: Val-40 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Reul and Holsboer (2002) Corticotropin-releasing factor receptors 1 and 2 in anxiety and depression. Curr.Opin.Pharmacol. 2 23. PMID: 11786305.
Skelton et al (2000) The neurobiology of urocortin. Regul.Pept. 93 85. PMID: 11033056.
Perrin and Vale (1999) Corticotropin releasing factor receptors and their ligand family. Ann.N.Y.Acad.Sci. 885 312. PMID: 10816663.
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Citations are publications that use Tocris products.
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Keywords: Urocortin (human), supplier, Endogenous, CRF, agonists, Corticotropin-Releasing, Factor, Non-Selective, Receptors, Tocris Bioscience, Non-selective CRF Receptor Agonist products