Cat. No. 2915
Chemical Name: Diphosphoric acid 1-α-D-glucopyranosyl ester 2-[(4'-methylthio)uridin-5''-yl] ester disodium salt
Biological ActivityPotent P2Y14 receptor agonist (EC50 = 49 nM) that displays 7-fold higher potency than UDP-glucose.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Ko et al (2007) Structure-activity relationship of uridine 5'-diphosphoglucose analogues as agonists of the human P2Y14 receptor. J.Med.Chem. 50 2030. PMID: 17407275.
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Citations are publications that use Tocris products. Selected citations for MRS 2690 include:
Gao et al (2013) The role of P2Y(14) and other P2Y receptors in degranulation of human LAD2 mast cells. Neuropsychopharmacology 9 31. PMID: 22825617.
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Keywords: MRS 2690, supplier, Potent, P2Y14, agonists, Receptors, Purinergic, purinoceptors, MRS2690, Tocris Bioscience, Purinergic (P2Y) Receptor Agonist products
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