ELA-14 (human)

Cat. No. 6293new

ELA-14 (human) Glp-Arg-Arg-Cys-Met-Pro-Leu-His-Ser-Arg-Val-Pro-Phe-Pro

Price and Availability

For ELA-14 (human) pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Names: ELA (19-32) (human), ELABELA

Biological Activity

Potent apelin (APJ) receptor agonist (Ki = 0.93 nM). ELABELA analog. Activates Gαil pathway and β-arrestin-2 recruitment . Reduces arterial pressure in rat hearts. Active in vivo. ELA-14 negative control (Cat.No. 6294) available.

Licensing Information

Sold under agreement from the Agency for Science, Technology and Research (A*STAR), ETPL, and affiliates including the Institute of Medical Biology.

Technical Data

M.Wt:
1707.03
Formula:
C75H119N25O17S2
Sequence:
XRRCMPLHSRVPFP

(Modifications: X = Glp)

Solubility:
Soluble to 1 mg/ml in water
Storage:
Store at -20°C
CAS No:
1886973-05-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Murza et al (2016) Discovery and structure-activity relationship of a bioactive fragment of ELABELA that modulates vascular and cardiac functions. J.Med.Chem. 59 2962. PMID: 26986036.

If you know of a relevant reference for ELA-14 (human) please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses ELA-14 (human) from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: ELA-14 (human), supplier, Apelin, receptor, agonist, agonism, APJ, ELABELA, analog, beta-arrestin-2, b-arrestin-2, β-arrestin-2, Gail, Galphail, Gαil, blood, pressure, active, in, vivo, Tocris Bioscience, Apelin Receptor Agonist products

Quick Order

Find multiple products by catalog number

divider line

Cardiovascular Research Product Guide

Cardiovascular Research Product Guide

Our Cardiovascular Guide highlights over 250 products for cardiovascular research. Request copy or view PDF today.

divider line

Peptide Hormone Receptors Product Listing

Peptide Hormone Receptors Product Listing

Our Peptide Hormone Receptors Listing highlights over 200 products for peptide hormone receptors. Request copy or view PDF today.

divider line

GPCR Product Listing

GPCR Product Listing

Highlights over 450 products for GPCRs. Request copy or view PDF today.

divider line

Cardiovascular Life Science Poster

Written by J.J. Maguire and A.P. Davenport

Cardiovascular Life Science Poster

Our Cardiovascular poster highlights the key G protein-coupled receptors involved in the regulation of vascular reactivity. Request copy or view PDF today.

divider line

New Products in this Area

ELARR>GG

Negative control for ELA-32 (Cat.No.6291).

ELA-32 (human)

Potent, high affinity apelin receptor agonist; stimulates angiogenesis

Parathyroid hormone (1-34) (bovine)

Parathyroid hormone (PTH) receptor agonist.

Parathyroid hormone (1-34) (rat)

Parathyroid hormone (PTH) receptor agonist

Peptide YY (3-36) human

NPY Y2 receptor agonist

ELA-14 negative control

Negative control for ELA-14 (Cat.No.6293).

Retrobradykinin

Reverse analog of Bradykinin

TASP 0390325

Potent and selective V1B receptor antagonist; orally bioavailable

Sign-up for new product e-alerts
divider line

Bio-Techne Events

GDR3545

6th Annual Meeting GDR3545

November 8 - 10, 2017

Paris, France