Cat. No. 1539
Alternative Name: β-PMTX
Biological ActivityNovel wasp neurotoxin that slows Na+ channel inactivation. Facilitates neuromuscular synaptic transmission and discriminates between rat neuronal and cardiac Na+ channel α-subunits.
Licensing InformationSold with the permission of Suntory Ltd.
(Modifications: Leu-13 = C-terminal amide)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Miyawaki et al (2002) Differential effects of novel wasp toxin on rat hippocampal interneurons. Neurosci.Lett. 328 25. PMID: 12123851.
Kinoshita et al (2001) Novel wasp toxin discriminates between neuronal and cardiac sodium channels. Mol.Pharmacol. 59 1457. PMID: 11353806.
Konno et al (1998) Isolation and structure of pompilidotoxins, novel peptide neurotoxins in solitary wasp venoms. Biochem.Biophys.Res.Commun. 250 612. PMID: 9784394.
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Keywords: beta-Pompilidotoxin, supplier, Slows, neuronal, Na+, channels, inactivation, Sodium, NaV, voltage-gated, voltage-dependent, beta-Pompilidotoxin, β-PMTX, beta-PMTX, neurotoxins, venoms, Tocris Bioscience, Voltage-gated Sodium (NaV) Channel products
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