Cat. No. 2837
Biological ActivityMember of the neurotrophin growth factor family that binds and activates TrkB and p75 neurotrophin receptors. Enhances the survival, growth and differentiation of neurons. BDNF expression is altered in neurodegenerative disorders such as Parkinson's and Alzheimer's disease.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Evans and Barker (2008) Neurotrophic factors as a therapeutic target for Parkinson's disease. Expert Opin.Ther.Targets 12 437. PMID: 18348680.
Wang et al (2008) The when and where of BDNF and the antidepressant response. Biol.Psychiat. 63 640.
Lipsky and Marini (2007) Brain-derived neurotrophic factor in neuronal survival and behavior-related plasticity. Ann.N.Y.Acad.Sci. 1122 130. PMID: 18077569.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products. Selected citations for BDNF (human) include:
Parsons et al (2014) Bidirectional control of postsynaptic density-95 (PSD-95) clustering by Huntingtin. J Biol Chem 289 3518. PMID: 24347167.
Do you know of a great paper that uses BDNF (human) from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: BDNF (human), supplier, activators, TrkB, p75, receptors, Neurotrophin, Receptors, Receptor, Tyrosine, Kinases, RTKs, Tocris Bioscience, Trk Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
Selective TrkB receptor agonist; neuroprotectantAV 412
Potent inhibitor of EGFR, ErbB2 and Abl receptor tyrosine kinasesCP 724714
Potent and selective ErbB2 inhibitorMitoglitazone
Insulin sensitizer; exhibits low binding affinity at PPARγPF 6274484
High affinity and potent covalent EGFR kinase inhibitorCanertinib dihydrochloride
Potent EGFR kinase inhibitorCHMFL-FLT3-122
Potent and selective FLT3 inhibitor
November 12 - 16, 2016
San Diego, CA, USA