Cat. No. 2759
Alternative Name: Talipexole
Chemical Name: 5,6,7,8-Tetrahydro-6-(2-propen-1-yl
Biological ActivityDopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist. Displays antiParkinsonian activity.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Maina and Mathews (2010) A functional fast scan cyclic voltammetry assay to characterize dopamine D2 and D3 autoreceptors in the mouse striatum. ACS Chem.Neurosci. 1 450. PMID: 20567609.
Ricci and Taira (1999) Adrenoceptor involvement in the cardiovascular responses to B-HT 920 in sinoaortic denervated rats. Gen.Pharmacol. 32 29. PMID: 9888250.
Nishio et al (1996) 5-HT3 receptor blocking properties of the antiParkinsonian agent, talipexole. Gen.Pharmacol. 27 779. PMID: 8842679.
Robertson et al (1993) In vivo comparisons of the effects of quinpirole and the putative presynaptic dopaminergic agonists B-HT 920 and SND 919 on striatal dopamine and acetylcholine release. J.Pharmacol.Exp.Ther. 264 1344. PMID: 8095550.
If you know of a relevant reference for B-HT 920 please let us know.
Citations are publications that use Tocris products. Selected citations for B-HT 920 include:
Otvos et al (2015) Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms. Autophagy 7 2336. PMID: 26114334.
Do you know of a great paper that uses B-HT 920 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: B-HT 920, supplier, 5-HT3, antagonists, D2, α2-adrenoceptor, alpha2-adrenoceptor, a2-adrenoceptor, a2-adrenergic, agonists, receptor, Serotonin, Receptors, Dopamine, dopaminergic, B-HT920, Tocris Bioscience, D2 Receptor Agonist products
Find multiple products by catalog number
New Products in this Area
G protein-biased D2 receptor partial agonist
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.