TBCA

Cat. No. 2825

TBCA C9H4Br4O2 [934358-00-6]

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Chemical Name: (2E)-3-(2,3,4,5-Tetrabromophenyl)-2-propenoic acid

Biological Activity

Selective CK2 inhibitor (IC50 = 110 nM). Exhibits selectivity for CK2 over CK1, DYRK1A and a panel of 27 other kinases. Reduces viability of Jurkat cells in vitro.

Technical Data

M.Wt:
463.74
Formula:
C9H4Br4O2
Solubility:
Soluble to 100 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
934358-00-6

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Pagano et al (2007) Tetrabromocinnamic acid (TBCA) and related compounds represent a new class of specific protein kinase CK2 inhibitors. Chembiochem. 8 129. PMID: 17133643.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for TBCA include:

Shi et al (2015) Acupuncture elicits neuroprotective effect by inhibiting NAPDH oxidase-mediated reactive oxygen species production in cerebral ischaemia. J Virol 5 17981. PMID: 26656460.

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Keywords: TBCA, supplier, selective, casein, kinases, CK2, inhibitors, inhibits, Tocris Bioscience, Casein Kinase 2 Inhibitor products

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