Cat. No. 2844
Chemical Name: 4-Amino-5-chloro-2-ethoxy-N-[[4-[(4
Biological Activity5-HT4 receptor agonist and 5-HT3 receptor antagonist. Displays no activity at D2, α1, α2, 5-HT1 and 5-HT2 receptors. Gastroprokinetic agent; increases gastric emptying in rats and stimulates gastric motor actvity in conscious dogs.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Mine et al (1997) Comparison of effect of mosapride citrate and existing 5-HT4 receptor agonists on gastrointestinal motility in vivo and in vitro. J.Pharmacol.Exp.Ther. 283 1000. PMID: 9399969.
Yoshida et al (1993) Pharmacological effects of the new gastroprokinetic agent mosapride citrate and its metabolites in experimental animals. Arzneim.-Forsch. 43 1078.
Yoshida et al (1989) AS-4370, a novel gastrokinetic agent free of dopamine D2 receptor antagonist properties. Arch.Int.Pharmacodyn.Ther. 300 51. PMID: 2533479.
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Keywords: Mosapride citrate, supplier, 5-HT3, antagonists, 5-HT4, agonists, Serotonin, Receptors, 5-Hydroxytryptamine, Tocris Bioscience, 5-HT4 Receptor Agonist products
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