Cat. No. 2839
Alternative Names: Keppra, UCB L059
Chemical Name: (2S)-(2-Oxopyrrolidin-1-yl)butyrami
Biological ActivityAntiepileptic that displays distinctive properties from conventional antiepileptic drugs. Displays potent seizure protection in animal models of chronic epilepsy but lacks activity in acute seizure models. Binds synaptic vesicle protein 2A (SV2A) and inhibits Na+-dependent Cl-/HCO3- exchange.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Smedt et al (2007) Levetiracetam: the profile of a novel anticonvulsant drug - part I: preclinical data. CNS Drug Rev. 13 43. PMID: 17461889.
Ueda et al (2007) Effect of levetiracetam on molecular regulation of hippocampal glutamate and GABA transporters in rats with chronic seizures induced by amygdalar FeCl3 injection. Brain Res. 1151 55. PMID: 17408599.
Lynch et al (2004) The synaptic vesicle protein SV2A is the binding site for the antiepileptic drug levetiracetam. Proct.Natl.Acad.Sci. USA 101 9861.
If you know of a relevant reference for this product please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Levetiracetam from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Levetiracetam, supplier, Anti-epileptic, binds, SV2A, Exocytosis, Endocytosis, Protein, Translocation, UCBL059, Tocris Bioscience, Translocation, Exocytosis & Endocytosis products
Find multiple products by catalog number
New Products in this Area
Activator of STING-dependent signaling3',3'-cGAMP sodium salt
STING agonist2',3'-cGAMP sodium salt
Endogenous high affinity STING agonistc-Di-AMP sodium salt
Endogenous STING and DDX41 agonist; activates STING-dependent signalingc-Di-GMP sodium salt
Endogenous STING and DDX41 agonist; activates STING-dependent signalingCPYPP
DOCK2-Rac1 interaction inhibitor
Follow Tocris on LinkedIn
Visit our LinkedIn page for the latest Tocris news, events and updates.