Carbamoylcholine chloride

Cat. No. 2810

Carbamoylcholine chloride C6H15ClN2O2 [51-83-2]

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Alternative Name: Carbachol

Chemical Name: (2-Hydroxyethyl)trimethylammonium chloride carbamate

Biological Activity

Cholinergic receptor agonist that is resistant to the action of cholinesterases. Blocks apoptosis in cerebellar granule neurons.

Technical Data

M.Wt:
182.65
Formula:
C6H15ClN2O2
Solubility:
Soluble to 100 mM in water and to 50 mM in DMSO
Storage:
Desiccate at RT
CAS No:
51-83-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Certificate of Analysis / Product Datasheet
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Yan et al (1995) Activation of muscarinic cholinergic receptors blocks apoptosis of cultured cerebellar granule neurons. Mol.Pharmacol. 47 248. PMID: 7870032.

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Citations are publications that use Tocris products. Selected citations for Carbamoylcholine chloride include:

Goswami et al (2015) Motilin Stimulates Gastric Acid Secretion in Coordination with Ghrelin in Suncus murinus. PLoS One 10 e0131554. PMID: 26115342.

Martin et al (2015) Endocannabinoids Mediate Muscarinic Acetylcholine Receptor-Dependent Long-Term Depression in the Adult Medial Prefrontal Cortex. Stem Cell Reports 9 457. PMID: 26648844.

Svalø et al (2015) Functional and molecular evidence for Kv7 channel subtypes in human detrusor from patients with and without bladder outflow obstruction. Front Cell Neurosci 10 e0117350. PMID: 25692982.

Hwangpo et al (2012) G Protein-regulated inducer of neurite outgrowth (GRIN) modulates Sprouty protein repression of mitogen-activated protein kinase (MAPK) activation by growth factor stimulation. J Biol Chem 287 13674. PMID: 22383529.

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