β-Estradiol

Cat. No. 2824

b-Estradiol C18H24O2 [50-28-2]

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Alternative Name: 17 β-Estradiol

Chemical Name: (17β)-Estra-1,3,5(10)-triene-3,17-diol

Biological Activity

Endogenous estrogen receptor (ER) agonist (Ki values are 0.12 and 0.13 nM for ERα and ERβ respectively). Also high affinity ligand at membrane estrogen GPR30 receptors. α-Estradiol (Cat. No. 2823) also available.

Technical Data

M.Wt:
272.38
Formula:
C18H24O2
Solubility:
Soluble to 100 mM in DMSO and to 75 mM in ethanol
Purity:
>99 %
Storage:
Store at RT
CAS No:
50-28-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

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Safety Data Sheet: View Safety Data Sheet

Thomas et al (2005) Identity of an estrogen membrane receptor coupled to a G protein in human breast cancer cells. Endocrinology 146 624. PMID: 15539556.

Kuiper et al (1997) Comparison of the ligand binding specificity and transcript tissue distribution of estrogen receptors α and β. Endocrinology 138 863. PMID: 9048584.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products. Selected citations for β-Estradiol include:

Leal et al (2012) p130Cas over-expression impairs mammary branching morphogenesis in response to estrogen and EGF. PLoS One 7 e49817. PMID: 23239970.

Do you know of a great paper that uses β-Estradiol from Tocris? If so please let us know.

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Keywords: b-Estradiol, supplier, Endogenous, ER, agonists, Estrogen, Receptors, GPR30, beta-Estradiol, b-estradiol, β-estradiol, 17, β-Estradiol, 17, b-estradiol, 17, beta-estradiol, GPER, Tocris Bioscience, Estrogen and Related Receptor Agonist products

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