FPR A14

Cat. No. 2826

FPR A14 C23H20N2O5 [329691-12-5]

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Chemical Name: 1,3-Benzodioxolane-5-carboxylic acid 4'-benzyloxy-3'-methoxybenzylidene hydrazide

Biological Activity

Formyl peptide receptor (FPR) agonist that potently activates neutrophils in vitro (EC50 values are 42 and 630 nM for neutrophil chemotaxis and Ca2+ mobilization respectively).

Technical Data

M.Wt:
404.42
Formula:
C23H20N2O5
Solubility:
Soluble to 100 mM in DMSO
Purity:
>99 %
Storage:
Store at RT
CAS No:
329691-12-5

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Schepetkin et al (2007) High-throughput screening for small molecule activators of neutrophils: Identification of novel N-formyl peptide receptor agonists. Mol.Pharmacol. 71 1061. PMID: 17229869.

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Citations are publications that use Tocris products. Selected citations for FPR A14 include:

Yan et al (2015) Stimulation of hepatocarcinogenesis by neutrophils upon induction of oncogenic kras expression in transgenic zebrafish. J Hepatol 63 420. PMID: 25828472.

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Keywords: FPR A14, supplier, Formyl, peptide, FPR, agonists, FPRA14, receptors, Tocris Bioscience, Formyl Peptide Receptor Agonist products

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