pep4c

Cat. No. 1596

pep4c Lys-Arg-Met-Lys-Val-Ala-Lys-Ser-Ala-Gln

Price and Availability

For pep4c pricing & availability please select your country from the drop down menu:
Submit
By clicking submit you agree to accept a cookie from Tocris Bioscience. For details, please read our privacy and cookie policy.

Alternative Name: GluR4cr

Biological Activity

Inactive control peptide analog of pep2m (Cat. No. 1595), a peptide inhibitor of the interaction between the C-terminus of the GluR2 (AMPA receptor) subunit and N-ethylmaleimide-sensitive fusion protein (NSF).

Technical Data

M.Wt:
1146.42
Formula:
C48H91N17O13S
Sequence:
KRMKVAKSAQ
Solubility:
Soluble to 1 mg/ml in water
Storage:
Desiccate at -20°C
CAS No:
243843-43-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Collingridge and Isaac (2003) Functional roles of protein interactions with AMPA and kainate receptors. Neurosci.Res. 47 3. PMID: 12941441.

Luscher et al (1999) Role of AMPA receptor cycling in synaptic transmission and plasticity. Neuron 24 649. PMID: 10595516.

Luthi et al (1999) Hippocampal LTD expression involves a pool of AMPARs regulated by the NSF-GluR2 interaction. Neuron 24 389. PMID: 10571232.

Noel et al (1999) Surface expression of AMPA receptors in hippocampal neurons is regulated by an NSF-dependent mechanism. Neuron 23 365. PMID: 10399941.

Nishimune et al (1998) NSF binding to GluR2 regulates synaptic transmission. Neuron 21 87. PMID: 9697854.

If you know of a relevant reference for this product please let us know.

Citations are publications that use Tocris products.

Do you know of a great paper that uses pep4c from Tocris? If so please let us know.

View Related Products by Target

View Related Products by Product Action

Keywords: pep4c, supplier, Inactive, control, peptide, 1595, Glutamate, AMPA, Receptors, iGlu, Ionotropic, Tocris Bioscience, AMPA Receptor products

Quick Order

Find multiple products by catalog number

divider line

Pain Research Product Guide

Pain Research Product Guide

Our Pain guide highlights over 280 products for Pain research. Request copy or view PDF today.

divider line

Learning and Memory

Written by Clea Warburton and Zafar Bashir

Learning & Memory Life Science Poster

Our Learning and Memory poster gives an overview of the cellular mechanisms underlying recognition memory and its links to long-term depression. Request copy or view PDF today.

divider line

Mechanisms of Addiction

Addiction Life Science Poster

Written by Prof David Nutt, this poster summarizes the brain circuits and neurotransmitter systems that are affected by the main classes of addictive drugs. Request copy or view PDF today.

divider line

Peripheral Sensitization

Written by Grant D. Nicol and Michael R. Vasko

Pain Life Science Poster

Our Peripheral Sensitization poster gives a summary of the excitatory and inhibitory signaling pathways involved in modulation of peripheral sensitization. Request copy or view PDF today.

divider line

Parkinson's disease: Neurobiology and Therapeutic Strategies

Written by Anthony H.V. Schapira

Parkinson's Life Science Poster

Our Parkinson's disease (PD) poster summarizes the neurobiology of the disease, and highlights current therapeutic treatments for symptomatic PD. Request copy or view PDF today.

divider line

Antidepressants - Current and Future Targets

Written by P. Skolnich et al

Depression Life Science Poster

Our Depression poster highlights presynaptic and postsynaptic targets for the potential treatment of major depressive disorder. Request copy or view PDF today.

divider line

Therapeutic Strategies in Schizophrenia

Written by J. Lieberman

Schizophrenia Life Science Poster

Our Schizophrenia poster higlights the targets and pathways representing the most promising strategies to pursue for novel drug development. Request copy today.

divider line

Alzheimer's Disease: Neurobiology and Drug Targets

Written by Alan Palmer

Alzheimer's Life Science Poster

Our Alzheimer's disease poster summarizes the structural and functional changes observed in the progression of this neurodegenerative disease. Request copy or view PDF today.

divider line

New Products in this Area

PEAQX tetrasodium salt

Potent NMDA receptor antagonist; NR2A selective

cis-6-Hydroxynorketamine hydrochloride

Metabolite of ketamine (Cat.No. 3131); antidepressive

Sign-up for new product e-alerts
divider line

Bio-Techne Events

One Day Symposium

Bio-Techne Symposium 2017

Epigenetic Regulation of Stem Cell Differentiation

March 1, 2017

Amsterdam, The Netherlands