D-Amphetamine sulfate

Cat. No. 2813

D-Amphetamine sulfate C9H13N.1/2H2SO4 [51-63-8]

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Alternative Name: Dextroamphetamine sulfate

Chemical Name: (+)-α-Methylphenethylamine hemisulfate salt

Biological Activity

CNS stimulant. Targets monoamine transporters to elevate synaptic levels of noradrenalin, dopamine and serotonin.

Technical Data

Soluble to 100 mM in water
>99 %
Desiccate at RT

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Certificate of Analysis / Product Datasheet
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References are publications that support the products' biological activity.

Rothman and Baumann (2006) Balance between dopamine and serotonin release modulates behavioral effects of Amphetamine-type drugs. Ann.N.Y.Acad.Sci. 1074 245. PMID: 17105921.

Barr et al (1999) Effects of withdrawal from an escalating dose schedule of d-Amphetamine on sexual behavior in the male rat. Pharmacol.Biochem.Behav. 64 597. PMID: 10548277.

Cartmell et al (1999) The metabotropic glutamate 2/3 receptor agonists LY354740 and LY379268 selectively attenuate phencyclidine versus d-Amphetamine motor behaviors in rats. J.Pharmacol.Exp.Ther. 291 161. PMID: 10490900.

If you know of a relevant reference for D-Amphetamine sulfate please let us know.

Citations are publications that use Tocris products. Selected citations for D-Amphetamine sulfate include:

Czysz et al (2015) Lateral diffusion of Gαs in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains. PLoS One 40 766. PMID: 25249058.

Ribeiro et al (2014) Metabotropic glutamate receptor 5 knockout promotes motor and biochemical alterations in a mouse model of Huntington's disease. Neuropsychopharmacology 23 2030. PMID: 24282028.

Soda et al (2013) DISC1-ATF4 transcriptional repression complex: dual regulation of the cAMP-PDE4 cascade by DISC1. Mol Psychiatry 18 898. PMID: 23587879.

Do you know of a great paper that uses D-Amphetamine sulfate from Tocris? If so please let us know.

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Keywords: D-Amphetamine sulfate, supplier, Induces, 5-HT, dopamine, noradrenaline, release, Serotonin, 5-Hydroxytryptamine, amphetamine, Tocris Bioscience, Dopaminergic-Related products

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