Cat. No. 2805
Alternative Name: Ro 5-2807
Chemical Name: 7-Chloro-1-methyl-5-phenyl-3H-1,4-b
Biological ActivityLigand at the GABAA receptor benzodiazepine modulatory site. Anxiolytic, anticonvulsant and sedative/hypnotic agent.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Sieghart et al (1994) Pharmacology of benzodiazepine receptors: an update. J.Psychiat.Neurosci. 19 24.
If you know of a relevant reference for Diazepam please let us know.
Citations are publications that use Tocris products. Selected citations for Diazepam include:
Czysz et al (2015) Lateral diffusion of Gαs in the plasma membrane is decreased after chronic but not acute antidepressant treatment: role of lipid raft and non-raft membrane microdomains. PLoS One 40 766. PMID: 25249058.
Ufuk et al (2015) In Vitro Assessment of Uptake and Lysosomal Sequestration of Respiratory Drugs in Alveolar Macrophage Cell Line NR8383. Pharm Res 32 3937. PMID: 26224396.
Do you know of a great paper that uses Diazepam from Tocris? If so please let us know.
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Keywords: Diazepam, supplier, Acts, benzodiazepine, modulatory, site, GABAA, Receptors, Ro52807, Tocris Bioscience, GABAA Receptor Benzodiazepine products
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November 8 - 10, 2017