Cat. No. 2784
Chemical Name: 5-Methyl-4-oxide-2-pyrazinecarboxyl
Biological ActivityAntilipolytic agent; lowers plasma free fatty acid (FFA), triglyceride (TG), glucose and insulin levels and increases leptin levels.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Wang-Fisher et al (2002) Acipimox stimulates leptin production from isolated rat adipocytes. J.Endocrinol. 174 267. PMID: 12176665.
Christie et al (1996) Mechanism of anti-lipolytic action of acipimox in isolated rat adipocytes. Diabetol. 39 45.
Lovisolo et al (1981) Pharmacological proflie of a new antilipolytic agent: 5-methyl-pyrazine-2-carboxylic acid 4-oxide (acipimox) II - Antilipolytic and blood lipid lowering activitiy Pharmacol.Res.Comms. 13 163.
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Citations are publications that use Tocris products.
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Keywords: Acipimox, supplier, Antilipolytic, agent, Lipid, Metabolism, Tocris Bioscience, Other Lipid Metabolism products