cis VH 298
Cat. No. 6157
Chemical Name: (2S,4S)-1-((S)-2-(1-cyanocyclopropa
Biological ActivityNegative control for VH 298 (Cat.No. 6156). Exhibits no detectable binding of VHL.
Licensing InformationSold under licence from the University of Dundee
External Portal InformationChemicalprobes.org is a portal that offers independent guidance on the selection and/or application of small molecules for research. The use of VH 298 is reviewed on the chemical probes website.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Frost et al (2016) Potent and selective chemical probe of hypoxic signalling downstream of HIF-α hydroxylation via VHL inhibition. Nat.Commun. 7 13312. PMID: 27811928.
If you know of a relevant reference for cis VH 298 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses cis VH 298 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: cis VH 298, supplier, Inhibitors, Inhibition, VHL, HIF-alpha, HIF-a, HIF-α, VH298, cisVH298, von, Hippel-Lindau, protein, E3, uniquitin, ligase, Tocris Bioscience, Ubiquitin E3 Ligase Inhibitor products
Find multiple products by catalog number
New Products in this Area
Cereblon ubiquitination inhibitor; also TNFα inhibitor and antiangiogenicLenalidomide
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligaseVH 298
High-affinity inhibitor of VHLcis MZ 1
Negative Control for MZ1MZ 1
(+)-JQ1 based PROTAC that selectively degrades BRD4 in cells.
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.