Naproxen sodium

Cat. No. 2655

Naproxen sodium C14H13NaO3 [26159-34-2]

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Chemical Name: (2S)-2-(6-Methoxy-2-naphthyl)propanoic acid sodium salt

Biological Activity

Non-selective cyclooxygenase (COX) inhibitor that displays anti-inflammatory, antipyretic and analgesic effects. Has a neuroprotective role against colchicine-induced cognitive impairment and oxidative stress.

Technical Data

M.Wt:
252.24
Formula:
C14H13NaO3
Solubility:
Soluble to 100 mM in water
Purity:
>99 %
Storage:
Desiccate at RT
CAS No:
26159-34-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Dhir et al (2006) Protective effect of naproxen (non-selective COX-inhibitor) or rofecoxib (selective COX-2 inhibitor) on immobilization stress-induced behavioral and biochemical alterations in mice. Eur.J.Pharmacol. 535 192. PMID: 16522321.

Kumar et al (2006) Differential effects of cyclooxygenase inhibitors on intracerebroventricular colchicine-induced dysfunction and oxidative stress in rats. Eur.J.Pharmacol. 551 58. PMID: 17027965.

Sutton (1996) Naproxen sodium. J.Am.Pharm.Assoc. (Wash) NS36 633. PMID: 8952250.

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Keywords: Naproxen sodium, supplier, Cyclooxygenase, inhibitors, inhibits, COX, Oxygenases, Oxidases, oxidative, stress, Tocris Bioscience, Cyclooxygenase Inhibitor products

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