Cat. No. 6117
Chemical Name: Tricarbonyldichlororuthenium(II) dimer
Biological ActivityCarbon monoxide-releasing molecule. Causes vasodilatation in isolated aortic rings in vitro. Cytotoxic to smooth muscle cells in vitro after prolonged (24h) exposure. Exhibits antihypertensive effects in vivo. Reduces tight-junction disruption in intestinal mucosa in a rat sepsis model.
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Certificate of Analysis / Product Datasheet / Safety Datasheet
Zhang et al (2015) Carbon monoxide-releasing molecule-2 reduces intestinal epithelial tight-junction damage and mortality in septic rats. PLoS One 10 e0145988. PMID: 26720630.
Motterlini et al (2002) Carbon monoxide-releasing molecules: characterization of biochemical and vascular activities. Circ.Res. 90 E17. PMID: 11834719.
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Keywords: CORM 2, supplier, CORM2, CO, carbon, monoxide, releasing, moleculea, antihypertensives, vasorelaxant, Tocris Bioscience, ROS and Other Gaseous Donor products
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