Cat. No. 2633
Chemical Name: N-[2-[4-[[[2-[(Hydroxyamino)carbony
Biological ActivityPotent and selective inhibitor of MMP-13 (IC50 values are 17, 945, > 1000 and > 10000 nM for MMP-13, MMP-9, TACE and MMP-1 respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Jaffré et al (2012) ß-adrenergic receptor stimulation transactivates protease-activated receptor 1 via matrix metalloproteinase 13 in cardiac cells. Circulation 125 2993. PMID: 22610965.
Chen et al (2000) Structure-based design of a novel, potent, and selective inhibitor for MMP-13 utilizing NMR spectroscopy and computer-aided molecular design. J.Am.Chem.Soc. 122 9648.
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Keywords: WAY 170523, supplier, Potent, selective, inhibitors, inhibits, MMP-13, Matrix, Metalloprotease, Matrixins, Metalloproteinase, MMP, Proteinases, Proteases, WAY170523, Tocris Bioscience, Matrix Metalloprotease Inhibitor products
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