Cat. No. 2622
Chemical Name: (R)-N-Hydroxy-2-(N-isopropoxybiphen
Biological ActivitySelective inhibitor of MMP-2 that displays ~ 600-fold selectivity over MMP-1 (IC50 values are 0.81 and 486 nM respectively).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Safety Data Sheet
Tuccinardi et al (2006) Amber force field implementation, molecular modelling study, synthesis and MMP-1/MMP-2 inhibition profile of (R)- and (S)-N-hydroxy-2-(N-isopropoxybiphenyl-4-ylsulfonamido)-3 methylbutanamides. Bioorg.Med.Chem. 14 4260. PMID: 16483784.
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Keywords: ARP 101, supplier, inhibitors, inhibits, MMP-2, Matrix, Metalloprotease, Matrixins, Metalloproteinase, MMP, Proteinases, Proteases, ARP101, Tocris Bioscience, Matrix Metalloprotease Inhibitor products
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