Cat. No. 6086
Chemical Name: Adenosine-5'-[(β,γ)-imido]triphosphate
Biological ActivityNon-hydrolyzable AMP analog. Kir6 (KATP) channel blocker. Inhibits fast axonal transport and stabilizes the interaction of membranous organelles with microtubules.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Hehl and Neumcke (1994) KATP channels of mouse skeletal muscle: mechanism of channel blockage by AMP-PNP. Eur.Biophys.J. 23 231. PMID: 7805625.
Brady (1985) A novel brain ATPase with properties expected for the fast axonal transport motor. Nature 317 73. PMID: 2412134.
Yount et al (1971) Adenylyl imidodiphosphate, an adenosine triphosphate analog containing a P-N-P linkage. Biochemistry 10 2484. PMID: 4326768.
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Keywords: AMP PNP, supplier, AMPPNP, non-hydrolyzable, non-hydrolysable, AMP, analog, adenylyl-imidodiphosphate, tetralithium, salt, Kir6, channel, blockers, blocks, KATP, inward, rectifier, potassium, current, Tocris Bioscience, Inward Rectifier Potassium (Kir) Channel Blocker products