Cat. No. 6044
Chemical Name: 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone
Biological ActivityInduces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. Iron chelator and putative inhibitor of KDM5B.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Cao et al (2016) Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science 352 6290. PMID: 27127239 .
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Keywords: AS 8351, supplier, AS8351, stem, cells, cardiac, cardiomyocytes, reprogramming, iron, chelators, reprogramming, differentiation, KDM, Tocris Bioscience, Reprogramming products