Cat. No. 6044
Chemical Name: 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone
Biological ActivityInduces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. Iron chelator and putative inhibitor of KDM5B.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Cao et al (2016) Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science 352 6290. PMID: 27127239 .
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Keywords: AS 8351, supplier, AS8351, stem, cells, cardiac, cardiomyocytes, reprogramming, iron, chelators, reprogramming, differentiation, KDM, Tocris Bioscience, Reprogramming products
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