AS 8351

Cat. No. 6044new

AS 8351 C17H13N3O2 [796-42-9]

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Chemical Name: 2-Hydroxy-1-naphthaldehyde isonicotinoylhydrazone

Biological Activity

Induces reprogramming of human fetal lung fibroblasts into functional cardiomyocytes, in combination with CHIR 99021, A83-01, BIX 01294, SC1, Y-27632, OAC2, SU 16f and JNJ 10198409. Iron chelator and putative inhibitor of KDM5B.

Technical Data

Soluble to 100 mM in DMSO
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Cao et al (2016) Conversion of human fibroblasts into functional cardiomyocytes by small molecules. Science 352 6290. PMID: 27127239 .

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Keywords: AS 8351, supplier, AS8351, stem, cells, cardiac, cardiomyocytes, reprogramming, iron, chelators, reprogramming, differentiation, KDM, Tocris Bioscience, Reprogramming products

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80 Stem Cell modulators supplied pre-dissolved in DMSO

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Includes many of the latest compounds available for stem cell research. Covers compounds for stem cell differentiation, signaling and reprogramming.

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