Cat. No. 6031
Biological ActivityEndogenous calcitonin receptor agonist. Lowers systemic blood calcium levels and inhibits bone resorption.
(Modifications: Pro-32 = C-terminal amide, Disulfide bridge between 1 - 7)
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Bower and Hay (2016) Amylin structure-function relationships and receptor pharmacology: implications for amylin mimetic drug development. Br.J.Pharmacol. 173 1883. PMID: 27061187.
Lee et al (2016) Calcitonin and amylin receptor peptide interaction mechanisms. J.Biol.Chem. 291 16416. PMID: 27474777.
Foster (1968) Calcitonin. A review of experimental and clinical investigations. Postgrad.Med.J. 44 411. PMID: 4871775.
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Citations are publications that use Tocris products.
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Keywords: Calcitonin (human), supplier, endogenous, calcitonin, receptors, agonists, agonism, inhibits, bone, resorption, Tocris Bioscience, Calcitonin and Related Receptor Agonist products
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