Cat. No. 6008
Chemical Name: N-Methyl-N-((2-(1-(2-(methylamino)e
Biological ActivityPotent and selective PRMT4 inhibitor; inhibits methylation of H3 (1-25) and MED12 (IC50 values are <10 and 43 nM, respectively). Exhibits >100-fold selectivity over other histone methyltransferases and non-epigenetic targets.
Licensing InformationThis probe is supplied in conjunction with the Structural Genomics Consortium. For further characterization details, please visit the TP 064 probe summary on the SGC website.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
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Keywords: TP 064, supplier, TP064, Potent, allosteric, inhibitors, inhibits, of, protein, arginine, methyltransferase, 4, PRMT4, methylation, Tocris Bioscience, Protein Arginine Methyltransferase Inhibitor products
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Tocris has a collaboration with the Structural Genomics Consortium (SGC) to provide the latest high quality epigenetics probes.