Cat. No. 6002
Chemical Name: 3,4-Dihydro-6-hydroxy-2,5,7,8-tetra
Biological ActivityAntioxidant vitamin E derivative; suppresses osteoclast formation and inhibits IL-1-induced osteoclast bone loss. Cell-permeable and water soluble.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Data Sheet
Lee et al (2009) Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling. J.Biol.Chem. 284 13725. PMID: 19299513.
Giulivi et al (1993) Inhibition of protein radical reactions of ferrylmyoglobin by the water-soluble analog of vitamin E, Trolox C. Arch.Biochem.Biophys. 303 152. PMID: 8489259.
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Keywords: Trolox, supplier, Antioxidant, vitamin, E, derivatives, osteoclast, formation, loss, bone, Tocris Bioscience, Antioxidant products
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