Cat. No. 6002new

Trolox C14H18O4 [53188-07-1]

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Chemical Name: 3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-carboxylic acid

Biological Activity

Antioxidant vitamin E derivative; suppresses osteoclast formation and inhibits IL-1-induced osteoclast bone loss. Cell-permeable and water soluble.

Technical Data

Soluble to 100 mM in DMSO and to 100 mM in ethanol
>98 %
Store at +4°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Lee et al (2009) Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling. J.Biol.Chem. 284 13725. PMID: 19299513.

Giulivi et al (1993) Inhibition of protein radical reactions of ferrylmyoglobin by the water-soluble analog of vitamin E, Trolox C. Arch.Biochem.Biophys. 303 152. PMID: 8489259.

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Keywords: Trolox, supplier, Antioxidant, vitamin, E, derivatives, osteoclast, formation, loss, bone, Tocris Bioscience, Antioxidant products

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