Cat. No. 6002
Chemical Name: 3,4-Dihydro-6-hydroxy-2,5,7,8-tetra
Biological ActivityAntioxidant vitamin E derivative; suppresses osteoclast formation and inhibits IL-1-induced osteoclast bone loss. Cell-permeable and water soluble.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Lee et al (2009) Trolox prevents osteoclastogenesis by suppressing RANKL expression and signaling. J.Biol.Chem. 284 13725. PMID: 19299513.
Giulivi et al (1993) Inhibition of protein radical reactions of ferrylmyoglobin by the water-soluble analog of vitamin E, Trolox C. Arch.Biochem.Biophys. 303 152. PMID: 8489259.
If you know of a relevant reference for Trolox please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses Trolox from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: Trolox, supplier, Antioxidant, vitamin, E, derivatives, osteoclast, formation, loss, bone, Tocris Bioscience, Antioxidant products
Find multiple products by catalog number
New Products in this Area
Antiviral; active against Zika, West Nile and dengue viruses25-Hydroxycholesterol
Antiviral; also α-crystallin (cryAB) chaperoneFilipin III
Polyene antibiotic; inhibits formation of pathological isoform of prion protein
Win a $1,000 travel grant
Bio-Techne is offering 10 travel grants of $1,000 for ISSCR 2017.