Cat. No. 5966
Chemical Name: (E)-4-Methyl-5-(((phenylsulfonyl)ox
Biological ActivityNon-peptide apelin receptor agonist (EC50 = 3.7 μM); exhibits >21-fold selectivity over the closely related angiotensin 1 receptor (EC50 = >79 μM).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Yang et al (2015) Apelin, Elabela/Toddler, and biased agonists as novel therapeutic agents in the cardiovascular system. Trends Pharmacol Sci. 36 560. PMID: 26143239.
Khan et al (2011) Functional agonists of the apelin (APJ) receptor. Probe Reports from the NIH Molecular Libraries Program. PMID: 22834038.
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Keywords: ML 233, supplier, ML233, Potent, non, peptide, agonists, APJ, Receptors, Apelin, adipokines, Tocris Bioscience, Apelin Receptor Agonist products
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April 1 - 5, 2017
Washington, D.C., USA