Cat. No. 5965
Chemical Name: 4-(2-Furanyl)-4,10-dihydro-2-methyl
Biological ActivityHigh affinity A2B receptor antagonist (Ki = 3.49 nM). Exhibits >1000-fold selectivity for A2B over A1, A2A and A3 receptors.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
El Maatougui et al (2016) Discovery of potent and highly selective A2B adenosine receptor antagonist chemotypes. J.Med.Chem. 59 1967. PMID: 26824742.
If you know of a relevant reference for ISAM 140 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses ISAM 140 from Tocris? If so please let us know.
View Related Products by Product Action
Keywords: ISAM 140, supplier, ISAM140, high, affinity, adenosine, receptors, A2B, selective, Tocris Bioscience, Adenosine A2B Receptor Antagonist products
Find multiple products by catalog number
New Products in this Area
High affinity adenosine A1 receptor antagonist
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.