ISAM 140

Cat. No. 5965

ISAM 140 C19H19N3O3 [932191-62-3]

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Chemical Name: 4-(2-Furanyl)-4,10-dihydro-2-methylpyrimido[1,2-a]benzimidazole-3-carboxylic acid-1-methylethyl ester

Biological Activity

High affinity A2B receptor antagonist (Ki = 3.49 nM). Exhibits >1000-fold selectivity for A2B over A1, A2A and A3 receptors.

Technical Data

M.Wt:
337.37
Formula:
C19H19N3O3
Solubility:
Soluble to 20 mM in DMSO
Purity:
>98 %
Storage:
Store at -20°C
CAS No:
932191-62-3

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

El Maatougui et al (2016) Discovery of potent and highly selective A2B adenosine receptor antagonist chemotypes. J.Med.Chem. 59 1967. PMID: 26824742.

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Keywords: ISAM 140, supplier, ISAM140, high, affinity, adenosine, receptors, A2B, selective, Tocris Bioscience, Adenosine A2B Receptor Antagonist products

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