Desloratadine

Cat. No. 5958

Desloratadine C19H19ClN2 [100643-71-8]

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Chemical Name: 8-Chloro-6,11-dihydro-11-(4-piperidinylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine

Biological Activity

High affinity histamine H1 receptor antagonist (Ki = 0.87 nM); active metabolite of loratadine (Cat. No. 1944). Anti-inflammatory.

Technical Data

M.Wt:
310.82
Formula:
C19H19ClN2
Solubility:
Soluble to 20 mM in DMSO and to 100 mM in ethanol
Purity:
>99 %
Storage:
Store at +4°C
CAS No:
100643-71-8

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Data Sheet

Henz (2001) The pharmacologic profile of desloratadine: a review. Allergy 56 7. PMID: 11243504.

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Keywords: Desloratadine, supplier, histamine, H1, receptors, antagonists, histaminergic, anti-inflammatory, hay, fever, allergic, rhinitis, chornic, urticaria, Tocris Bioscience, Histamine H1 Receptor Antagonist products

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