Cat. No. 5943
Chemical Name: N-[(1R,3S,5S)-9-(2-((2-Chlorophenyl
Biological ActivityPotent and selective hCXCR6 antagonist (IC50 = 140 nM); 100-fold less active at the murine CXCR6 receptor (IC50 = 18 μM). Exhibits selectivity over CXCR5, CXCR4, CCR6 and APJ receptors (IC50 >79 μM).
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Hershberger et al (2012) Probing the CXCR6/CXCL16 Axis: targeting prevention of prostate cancer metastasis. Probe Reports from the NIH Molecular Libraries Program. PMID: 24049849.
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Keywords: ML 339, supplier, ML339, Potent, human, CXCR6, antagonists, antagonism, metastasis, Tocris Bioscience, Chemokine CXC Receptor Antagonist products