H2DCFDA

Cat. No. 5935

H2DCFDA C24H16Cl2O7 [4091-99-0]

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Chemical Name: 2-[3,6-Bis(acetyloxy)-2,7-dichloro-9H-xanthen-9-yl]benzoic acid

Biological Activity

Fluorescent ROS indicator; becomes fluorescent when oxidized. Excitation wavelength ~490 nm, emission ~520 nm. Cell permeable.

Technical Data

M.Wt:
487.29
Formula:
C24H16Cl2O7
Solubility:
Soluble to 100 mM in DMSO and to 10 mM in ethanol
Purity:
>97 %
Storage:
Store at -20°C
CAS No:
4091-99-0

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Santabárbara-Ruiz et al (2015) ROS-induced JNK and p38 signaling is required for unpaired cytokine activation during drosophila regeneration. PLoS Genet. 11 e1005595. PMID: 26496642.

Nicholson et al (2013) Sigma-2 receptors play a role in cellular metabolism: stimulation of glycolytic hallmarks by CM764 in human SK-N-SH neuroblastoma. J.Pharmacol.Exp.Ther. 356 232. PMID: 26574517.

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Citations are publications that use Tocris products.

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Keywords: H2DCFDA, supplier, Cell, permeable, fluorescent, probes, ROS, reactive, oxygen, species, indicators, dyes, Tocris Bioscience, Fluorescent Probe products

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