Tocriscreen Library of FDA-Approved Compounds
Cat. No. 5932
Biological ActivityA library of 160 FDA-approved compounds. Comprises a subset of the Tocriscreen Plus (Cat. No. 5840) compound library. Contains compounds covering a range of therapeutic classes e.g. the cardiovascular and nervous systems and research areas such as cancer and immunology. Includes both established gold-standard compounds, e.g. tamoxifen, paclitaxel, as well as more recent highly selective, targeted compounds, such as gefitinib and axitinib.
Key Format and Product Details
- All compounds are FDA-approved
- Full chemical and biological data available
- 96-well racks with Matrix storage tubes & SepraSeal caps
- Compounds arranged 80 per rack with 2 racks per library
- Pre-dissolved in 250 μL 10 mM DMSO solutions
- Compounds produced to same high chemical standard as Tocris catalog
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
on-line. Please contact Customer Service
References are publications that support the products' biological activity.
Li et al (2015) Small-molecule-driven direct reprogramming of mouse fibroblasts into functional neurons. Cell Stem Cell 17 195. PMID: 26253201.
Yu et al (2015) Small molecules enhance CRISPR genome editing in pluripotent stem cells. Cell Stem Cell 16 142. PMID: 25658371.
Edwards et al (2014) The University of New Mexico Center for Molecular Discovery. Comb.Chem.High Throughput Screen. 17 256. PMID: 24409953.
Li et al (2011) Generation of iPSCs from mouse fibroblasts with a single gene, Oct4, and small molecules. Cell Research 21 196. PMID: 20956998.
Beacham et al (2010) Cell-based potassium ion channel screening using the FluxORTM assay. J.Biomol.Screen. 15 44. PMID: 20208034..
Hattori et al (2010) Small-molecule screen identifies reactive oxygen species as key regulators of neutrophil chemotaxis. Proc.Natl.Acad.Sci.USA 107 3546. PMID: 20142487.
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Citations are publications that use Tocris products.
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