RS 09

Cat. No. 5928

RS 09 Ala-Pro-Pro-His-Ala-Leu-Ser

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Biological Activity

TLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.

Technical Data

M.Wt:
691.78
Formula:
C31H49N9O9
Sequence:
APPHALS
Solubility:
Soluble to 2 mg/ml in water
Storage:
Store at -20°C
CAS No:
1449566-36-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

Li et al (2016) Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 13 885. PMID: 26824411.

Shanmugam et al (2012) Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. PLoS One 7 e30839. PMID: 22363498.

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View Related Products by Product Action

Keywords: RS 09, supplier, RS09, TLR4, peptides, agonists, toll-like, receptors, agonism, adjuvants, Tocris Bioscience, Toll-like Receptor Agonist products

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