Cat. No. 5928
Biological ActivityTLR4 agonist. Promotes NF-κB nuclear translocation and induces inflammatory cytokine secretion in RAW264.7 macrophages in vitro. Acts as an adjuvant in vivo; enhances X-15 specific antibody serum concentrations, when administered with X-15-KLH in mice.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
Li et al (2016) Intranasal vaccination against HIV-1 with adenoviral vector-based nanocomplex using synthetic TLR-4 agonist peptide as adjuvant. Mol.Pharm. 13 885. PMID: 26824411.
Shanmugam et al (2012) Synthetic Toll like receptor-4 (TLR-4) agonist peptides as a novel class of adjuvants. PLoS One 7 e30839. PMID: 22363498.
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Keywords: RS 09, supplier, RS09, TLR4, peptides, agonists, toll-like, receptors, agonism, adjuvants, Tocris Bioscience, Toll-like Receptor Agonist products
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