pCPA methyl ester hydrochloride

Cat. No. 5871new

pCPA methyl ester hydrochloride C10H12ClNO2.HCl [14173-40-1]

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Chemical Name: 4-Chloro-DL-Phenylalanine methyl ester hydrochloride

Biological Activity

Tryptophan hydroxylase inhibitor. Inhibits 5-HT synthesis. Depletes 5-HT levels in orbitofrontal cortex and impairs reversal learning in rats. Methyl ester of p-Chlorophenylalanine (Cat. No. 0938).

Technical Data

Soluble to 100 mM in water and to 100 mM in DMSO
>98 %
Store at -20°C

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Safety Data Sheet

Certificate of Analysis: View current batch
Safety Data Sheet: View Safety Data Sheet

Pinto Brod et al (2016) Involvement of monoaminergic system in the antidepressant-like effect of (octylseleno)-xylofuranoside in the mouse tail suspension test. Prog.Neuropsychopharmacol.Biol.Psychiatry. 65 201. PMID: 26596986.

Wallace et al (2014) Vortioxetine restores reversal learning impaired by 5-HT depletion or chronic intermittent cold stress in rats. Int.J.Neuropsychopharmacol. 17 1695. PMID: 24852131.

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Keywords: pCPA methyl ester hydrochloride, supplier, tryptophan, hydroxylase, inhibitors, inhibits, serotonin, 5-HT, depletion, depletes, synthesis, Tocris Bioscience, Hydroxylase Inhibitor products

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