Cat. No. 5867
Chemical Name: 5-[(2-Benzothiazolylthio)methyl]-2,
Biological ActivitySelective MRP (multidrug resistance-associated protein) 4 inhibitor (IC50 = 2.6 μM). Selective for MRP4 over P-gp, MRP1 and ABCG2. Sensitizes MRP4 over-expressing cells to SN 38 (Cat. No. 2684).
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Cheung et al (2014) High-throughput screening identifies Ceefourin 1 and Ceefourin 2 as highly selective inhibitors of multidrug resistance protein 4 (MRP4). Biochem.Pharmacol. 91 97. PMID: 24973542.
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Keywords: Ceefourin 1, supplier, multidrug, resistance-associated, protein, 4, MRP4, inhibitors, inhibits, transporter, Tocris Bioscience, Multidrug Transporter Inhibitor products