Cat. No. 5865
Chemical Name: N-Cyclohexyl-N-(2-phenylethyl)-4-[4
Biological ActivityPotent DDHD2 inhibitor (IC50 = 1.3 nM). Selective for DDHD2 over 40 other serine hydrolases, but does exhibit cross-reactivity with ABHD6. Active n vivo. Increases brain triacylglycerol levels in mice.
Licensing InformationSold under license from The Scripps Research Institute
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Inloes et al (2014) The hereditary spastic paraplegia-related enzyme DDHD2 is a principal brain triglyceride lipase. Proc.Natl.Acad.Sci.U.S.A. 111 14924. PMID: 25267624 .
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Keywords: KLH 45, supplier, KLH45, DDHD2, inhibits, inhibitors, potent, in, vivo, active, serine, hydrolase, Tocris Bioscience, Other Hydrolase Inhibitor products
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