Cat. No. 5853
Chemical Name: 3-Bromo-4-[2-fluoro-4-[[4-oxo-2-[[2
Biological ActivityDGAT2 inhibitor (IC50 = 140 nM). Exhibits >70-fold selectivity for DGAT2 over DGAT1 and MGAT2.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Irshad et al (2017) Diacylglycerol acyltransferase 2 links glucose utilization to fatty acid oxidation in the brown adipocytes. J.Lipid Res. 58 15. PMID: 27836993.
Qi et al (2012) The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2 J.Lipid Res. 53 1106. PMID: 22493088.
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Keywords: JNJ DGAT2-A, supplier, JNJDGAT2-A, Diacylglycerol, O-Acyltransferases, DGAT2, inhibitors, inhibits, DGAT-2iJ, Tocris Bioscience, Diacylglycerol O-Acyltransferase Inhibitor products
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