Cat. No. 5849
Chemical Name: 3-[2-(5,6,7,8-Tetrahydro-5,5,8,8-te
Biological ActivitySynthetic analogue of all trans-retinoic acid. Promotes differentiation of human embryonal carcinoma (EC) cells primarily into epithelial-like cells, along with a small number of neurons.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Clemens et al (2013) The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. Mol.Biosyst. 9 677. PMID: 23364809.
Christie et al (2008) Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org.Biomol.Chem. 6 3497. PMID: 19082150 .
If you know of a relevant reference for EC 19 please let us know.
Citations are publications that use Tocris products.
Do you know of a great paper that uses EC 19 from Tocris? If so please let us know.
View Related Products by Target
View Related Products by Product Action
Keywords: EC 19, supplier, EC19, synthetic, all-trans, retinoic, acid, receptors, ATRA, differentiation, stem, cells, retinoids, Tocris Bioscience, Retinoic Acid Receptor products
Find multiple products by catalog number
New Products in this Area
Synthetic progesterone analogC-DIM 12
Nurr1 activator; inhibits NF-κB-dependent gene expression(S)-Equol
Potent estrogen receptor β (ERβ) agonistAilanthone
Potent inhibitor of androgen receptor (AR)(±)-ML 209
RORγt inverse agonist; suppresses Th17 cell differentiationAGN 193109
High affinity pan-RAR antagonistSR 9243
Selective LXR inverse agonist
Follow @Tocris on Twitter
Tocris is now actively tweeting. For regular updates on news, events and special offers, follow @Tocris on Twitter.