EC 19

Cat. No. 5849

EC 19 C23H24O2 [1010694-08-2]

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Chemical Name: 3-[2-(5,6,7,8-Tetrahydro-5,5,8,8-tetramethyl-2-naphthalenyl)ethynyl]benzoic acid

Biological Activity

Synthetic analogue of all trans-retinoic acid. Promotes differentiation of human embryonal carcinoma (EC) cells primarily into epithelial-like cells, along with a small number of neurons.

Technical Data

M.Wt:
332.44
Formula:
C23H24O2
Solubility:
Soluble to 50 mM in DMSO
Purity:
>98 %
Storage:
Store at +4°C
CAS No:
1010694-08-2

The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.

Certificate of Analysis / Product Datasheet / Safety Datasheet

References are publications that support the products' biological activity.

Clemens et al (2013) The action of all-trans-retinoic acid (ATRA) and synthetic retinoid analogues (EC19 and EC23) on human pluripotent stem cells differentiation investigated using single cell infrared microspectroscopy. Mol.Biosyst. 9 677. PMID: 23364809.

Christie et al (2008) Synthesis and evaluation of synthetic retinoid derivatives as inducers of stem cell differentiation. Org.Biomol.Chem. 6 3497. PMID: 19082150 .

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Citations are publications that use Tocris products.

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Keywords: EC 19, supplier, EC19, synthetic, all-trans, retinoic, acid, receptors, ATRA, differentiation, stem, cells, retinoids, Tocris Bioscience, Retinoic Acid Receptor products

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