Cat. No. 5824
Chemical Name: 4-[6-(4-Methyl-1-piperazinyl)[2,6'-b
Biological ActivityFluorescent dye. Binds the minor groove of DNA at A and T rich regions. Can be used as indicator of apoptosis.
The technical data provided above is for guidance only. For batch specific data refer to the Certificate of Analysis.
All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Oberhammer et al (1993) Apoptotic death in epithelial cells: cleavage of DNA to 300 and/or 50 kb fragments prior to or in the absence of internucleosomal fragmentation. EMBO J. 12 3679. PMID: 8253089.
Jin and Breslauer (1988) Characterization of the minor groove environment in a drug-DNA complex: bisbenzimide bound to the poly[d(AT)].poly[d(AT)]duplex. Proc.Natl.Acad.Sci.U.S.A. 85 8939. PMID: 2461559 .
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Citations are publications that use Tocris products.
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Keywords: Hoechst 33258, supplier, DNA, minor, groove, binds, fluorescent, dyes, probes, Tocris Bioscience, Fluorescent Dye products
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