Cat. No. 5804
Chemical Name: (1E,4S,5E,7R,9E,11aR,14S,14aR,15S,1
Biological ActivityAntibiotic; preferentially induces apoptosis in chronic lymphocytic leukemia (CLL) cells over normal B cells. Inhibits actin polymerization and leads to the accumulation of cells in G2 phase.
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All Tocris products are intended for laboratory research use only.
Certificate of Analysis / Product Datasheet / Safety Datasheet
References are publications that support the products' biological activity.
Knudsen et al (2014) Chaetoglobosin A preferentially induces apoptosis in chronic lymphocytic leukemia cells by targeting the cytoskeleton. Leukemia 28 1289. PMID: 24280868.
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Keywords: Chaetoglobosin A, supplier, Antibiotics, induces, apoptosis, inducer, selective, chronic, lymphocytic, leukemia, CLL, actin, polymerisation, inhibitor, inhbits, Tocris Bioscience, Antibiotic products
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